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The Czech – Norwegian Research Programme aims to enhance basic and applied research and cooperation between the partner scientific institutions by bilateral financial support. The programme operator in the Czech Republic is the Ministry of Education, Youth and Sports and the donor programme partner in Norway is the Research Council of Norway.

Laboratory of the Biology and Pathology of the Eye at The Charles University in Pragueobtained financial support from the Czech – Norwegian Research Programme for the project:

Tissue engineering of genetically competent corneal/conjunctival cells for subsequent grafting in human medicine.

Project ID: 7F14156, acronym:EYEFORTX

Project Partners:

  • Department of Ophthalmology, University Hospital Kralovske Vinohrady, Prague, Pavel Studený, MD. PhD.
  • Department of Ophthalmology, Oslo University Hospital, Oslo, Prof. Bjørn Nicolaissen, MD., PhD. and Department of Nutrition, Oslo University, Prof. Andrew R. Collins, PhD, ScD. as subcontractor.
  • Health Effects Laboratory, Environmental Chemistry Department, NILU-Norwegian Institute for Air Research, Kjeller, Dr. Mária Dušinská, PhD.


The overall project objective:

Transplantation medicine in the area of ophthalmosurgery is facing two significant problems; the shortage of donor tissues and their relatively short ’shelf life’. During this project we aim to develop novel improved protocols for the preparation of corneal (endothelial and epithelial) and conjunctival (epithelial and goblet) cells for potential grafting in human medicine. The project consists of four main parts:


  • Characterization and cultivation of corneal endothelial cells and engineering of grafts
  • Reparation and potential self-regeneration of corneal endothelial cells
  • Corneal, limbal and conjunctival cells: organ culture and engineering of grafts
  • Testing DNA stability in cells from cornea and related tissues



Principal Investigator: Katerina Jirsova, PhD.

E-mail: katerina.jirsova@lf1.cuni.cz, tel: 0022496 7238

Project Administrator: Kristyna Matejkova, DiS.

E-mail: kristyna.matejkova@lf1.cuni.cz, tel: 0022496 4264


EEA and Norwey grants: http://eeagrants.org/programme/view/CZ09/PA23

Project Promoter: www.cuni.cz

Project Information in Czech: http://www.eeagrants.cz/en/programmes/norway-grants-2009-2014/cz09-czech-norwegian-research-programme/cz09-approved-projects/tissue-engineering-of-genetically-compet-1543

Project Information in English: http://www.eeagrants.cz/cs/programy/norske-fondy-2009-2014/cz09-cesko-norsky-vyzkumny-program/cz09-schvalene-projekty/priprava-geneticky-stabilnich-bunek-roho-1543